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对超声波辅助提取甜葫芦中葫芦素B的工艺进行研究。在单因素试验的基础上，通过正交试验优化葫芦素B的提取条件，确定甜葫芦中葫芦素B超声波辅助提取的最佳工艺为料液比1∶10，甲醇体积分数70%，提取时间15 min，超声波功率500 W，此条件下葫芦素B得率为0.799%。“,”The extraction technology with ultrasonic of cucurbitacin B from sweet gourd is studied. Based on the single factor experiment, the extraction conditions with ultrasonic have been optimized by orthogonal analysis. The optimum extraction conditions are as follows: the rate of solid to solution 1∶10, the concentration of methanol 70%, the extraction time 15 min, the ultrasonic power 500 W, the yield of cucurbitacin B is 0.799%.