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铁是红细胞合成血红素必不可少的物质,吸收到骨髓的铁质,进入骨髓幼红细胞,聚集于线粒体中,与原卟啉结合形成血红素,后者再与球蛋白结合而成为血红蛋白,进而发育成为成熟红细胞[1]。缺铁性贫血(IDA)是由于体内缺乏铁质,影响血红蛋白合成而引起的一种贫血症,其发病率达到世界人口的10%~20%,也是我国最常见的贫血类型[2],我国约有2亿人患有缺铁性贫血和铁营养不良症,其中妇女、儿童为高发人群。IDA的治疗,一是去除缺铁病因,二是补充铁剂,临床上可依据病因病情选择口服铁剂或注射用铁剂。本文就铁剂的临床应用作一简介。
Iron is essential for the synthesis of heme red blood cells, absorbed into the bone marrow iron, into the bone marrow erythroblasts, gathered in the mitochondria, and the protoporphyrin to form heme, the latter combined with globulin and hemoglobin, which in turn Development of mature red blood cells [1]. Iron deficiency anemia (IDA) is a form of anemia caused by the lack of iron in the body that affects hemoglobin synthesis, and its incidence is 10% to 20% of the world’s population, and is also the most common type of anemia in China [2]. Our country About 200 million people suffer from iron-deficiency anemia and iron deficiency disorders, of which women and children are at high risk. IDA treatment, one is to remove the cause of iron deficiency, the second is iron supplementation, clinically based on the etiology of choice of oral iron or iron for injection. This article on the clinical application of iron for a brief introduction.