本文培养了80名井下铀矿工和20名男性健康对照者的外周血淋巴细胞,分析了染色体畸变率与暴露量的关系。作者采用0.3毫升全血微量培养法,细胞在36.0～36.5℃培养68～72小时,中止培养前2小时加0.2微克/毫升的秋水仙碱,用0.075M氯化钾处理细胞,常规制片。对个别疑似染色体嵌合体及畸形细胞做了胰蛋白酶G带和C带。 In this paper, peripheral blood lymphocytes of 80 underground uranium miners and 20 healthy controls were cultured, and the relationship between chromosome aberration rate and exposure was analyzed. The authors used 0.3 ml whole blood micro-culture method, the cells were cultured at 36.0 ~ 36.5 ℃ for 68 ~ 72 hours, suspended 2 hours before culture plus 0.2 micrograms / ml of colchicine, with 0.075M potassium chloride treatment of cells, conventional production. Trypsin G band and C band were made on some suspected chromosome chimeras and deformity cells.