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关于支气管腺瘤的恶变问题,多年来一直有不少争论.1930年,Kramer 在临床病例报告中首次提出支气管腺瘤恶变的可能性。然而,20世纪初期一向把它看作良性肿瘤,认为恶变只是偶然现象。至60年代,Goodner 等几篇论文对许多病例进行长期随访,开始建立支气管腺瘤是恶性肿瘤的观念。对治痔本病也有一些争论,有主张用支气管镜检切
With regard to the malignant transformation of bronchial adenomas, there have been many disputes over the years. In the 1930s, Kramer first proposed the possibility of malignant transformation of bronchial adenomas in clinical case reports. However, in the early 20th century, it was always regarded as a benign tumor, and it was considered that the malignant change was just an accidental phenomenon. By the 1960s, Goodner et al. had a long-term follow-up of many cases and began to establish the concept that bronchial adenomas are malignant. There is also some controversy over the treatment of this disease, there are advocates using bronchoscopy