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目的探讨提高原发性十二指肠癌早期诊断率及治疗效果的方法。方法回顾性分析1991年1月至2000年3月经手术及病理证实的21例原发性十二指肠癌的诊断及治疗。结果实施胰头十二指肠切除术9例,切除率43%,12例行姑息性胃空肠和(或)胆肠吻合。9例行胰头十二指肠切除术者中,7例获得随访,5例术后平均生存2.3年,2例术后生存至今,分别已15、19个月。12例姑息手术者,10例术后平均生存7.8个月。结论上消化道钡餐、CT 和纤维十二指肠镜检查是原发性十二指肠癌的主要诊断手段。原发性十二指肠癌多发生于十二指肠第二段、第三段,手术切除治疗效果优于姑息性手术治疗。
Objective To explore ways to improve the early diagnosis and treatment of primary duodenal cancer. Methods The diagnosis and treatment of 21 cases of primary duodenal cancer confirmed by surgery and pathology from January 1991 to March 2000 were retrospectively analyzed. Results The implementation of pancreatoduodenectomy in 9 cases, resection rate of 43%, 12 cases of palliative gastrojejunostomy and (or) choledochojejunostomy. Of the 9 patients who underwent pancreatoduodenectomy, 7 were followed up, and 5 had an average survival of 2.3 years after operation. The two patients survived 15 and 19 months respectively. Twelve patients underwent palliative surgery and 10 patients survived an average of 7.8 months after surgery. Conclusion Upper gastrointestinal barium meal, CT and fiber duodenoscopy are the main diagnostic methods for primary duodenal cancer. Primary duodenal cancer occurred in the second and third segments of the duodenum. Surgical resection was superior to palliative surgery.