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目的:观察甘精胰岛素联合二甲双胍治疗2型糖尿病的疗效。方法:将115例2型糖尿病患者按照随机数字表法分为观察组(57例)和对照组(58例),观察组在二甲双胍基础上应用甘精胰岛素,对照组在二甲双胍基础上给予诺和灵N。结果:观察组患者血糖达标时间、餐后2h血糖、糖化血红蛋白、夜间低血糖发生率均低于对照组,P<0.05。结论:甘精胰岛素联合二甲双胍治疗2型糖尿病,安全有效,值得临床借鉴。
Objective: To observe the efficacy of insulin glargine and metformin in the treatment of type 2 diabetes mellitus. Methods: One hundred and fifteen patients with type 2 diabetes were divided into observation group (57 cases) and control group (58 cases) according to the random number table. The observation group was given insulin glargine on the basis of metformin, while the control group was given norah on the basis of metformin Ling N Results: The observed time of blood glucose, 2h postprandial blood glucose, glycosylated hemoglobin and nocturnal hypoglycemia in observation group were lower than those in control group (P <0.05). Conclusion: Glargine and metformin are safe and effective for type 2 diabetes mellitus, which is worthy of clinical reference.