目的研究复方左旋多巴联合答是美治疗 30例帕金森病的疗效及安全性。　方法采用开放性自身对照研究方法 ,并以改良的Webster、试行的UPDRS评分标准及病人日记进行观察。　结果与单用复方左旋多巴比较 ,加用答是美治疗 6周后 ,“开”期潜伏期缩短 2 6 .3min ,“开”期持续时间增加 2 .9h ,平均总有效率为 6 0 .0 % ,结果有非常显著性差异 ,不良反应轻微而少见。　结论答是美是一种既有效又安全的新型抗帕金森病药物 Objective To study the efficacy and safety of compound levodopa in treating 30 Parkinson’s disease patients in the United States. METHODS: An open-ended, self-controlled study was used and was followed by a modified Webster, a trial-based UPDRS score, and a patient diary. Results Compared with compound levodopa alone, the answer was that after 6 weeks of treatment, the incubation period of “open” period was shortened 26.3min, the duration of “on” period was increased 2.9g, and the average total effective rate was 60. 0%, the results have very significant differences, minor and rare adverse reactions. Conclusion The answer is that the United States is a new effective and safe anti-Parkinson’s disease drugs