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血管紧张素Ⅱ的大部分心血管效应是由血管紧张素Ⅱ1型受体介导,但是越来越多的研究显示:血管紧张素Ⅱ2型受体具有拮抗AT1的功能,并被认为其可能是一种潜在的心脏、血管保护性受体。血管紧张素Ⅳ及其4型受体发挥着与经典血管紧张素Ⅱ不同甚至相反的生物学功能。
Most of the cardiovascular effects of angiotensin II are mediated by angiotensin II type 1 receptors, but more and more studies show that angiotensin II type 2 receptor antagonizes the function of AT1 and is believed to be probably A Potential Heart, Vasoprotective Receptor. Angiotensin IV and its receptor type 4 play a different and even opposite biological function than classical angiotensin II.