目的观察梭形细胞血管内皮瘤的临床病理特征和生物学行为，探索这一。近年来提出的肿瘤是否为一独立类型及其预后。方法运用组织病理学、免疫组织化学和随访观察资料，研究本瘤的诊断标准、鉴别诊断要点和良恶性。结果本瘤见于各种年龄组，男女性别无显著差异。病变位于真皮和皮下。组织学上由梭形细胞区和海绵状血管区组成。梭形细胞区主要成分为梭形细胞，也可见一些上皮样细胞。5例病人做了第八因子相关抗原和荆豆素的免疫组织化学。两者均在海绵状血管的内皮细胞呈阳性结果。而在校形细胞区，两者各有4例呈微弱阳性，各有1例明显阳性。8例病人获随访结果，其中5例在原部位有l－3次复发，但无1例转移。结论我们认为梭形细胞血管内皮瘤是一新的独立类型的血管肿瘤，可能是良性的。其“高复发率”可能与肿瘤多灶性和浸润性生长而难以切除干净有关。 Objective To observe the clinicopathological features and biological behaviors of spindle cell-shaped hemangioendothelioma and explore this. The tumors proposed in recent years are an independent type and its prognosis. Methods Histopathological, immunohistochemical and follow-up observation data were used to study the diagnostic criteria, differential diagnosis points, and benign and malignant of this tumor. Results The tumor was found in various age groups, with no significant differences between men and women. Lesions are located in the dermis and subcutaneously. Histologically, it consists of a spindle cell area and a cavernous vascular area. Spindle cells are mainly composed of spindle cells and some epithelioid cells are also seen. Five patients had performed immunohistochemistry on the VIII factor-associated antigen and quinolinone. Both were positive in the endothelial cells of the cavernous vessels. In the shape-formed cell area, 4 cases were slightly positive, and 1 case was significantly positive. Eight patients received follow-up results, of which 5 had recurrences in the original site, but none had metastasis. Conclusion We believe that spindle cell hemangioendothelioma is a new type of vascular tumor that may be benign. Its “high recurrence rate” may be related to the multifocal and invasive growth of tumors that are difficult to remove.