近年来,靶向制剂的研究开发已经成为一个全球性的热点,其中药物脂质体的研究已取得了突破性的进展。脂质体(Liposomes)是将药物包封入类脂双分子层形成的超微型球体,根据结构类型,可分成单室脂质体、多室脂质体和多相脂质体。1965年,英国Banghan等将磷脂悬浮于水中第一次制得了脂质体。1969年Huang应用超声法制得脂质 In recent years, the research and development of targeted agents has become a global hot spot, and breakthroughs have been made in the research of drug liposomes. Liposomes are nanospheres that encapsulate drugs into lipid bilayers and can be separated into single compartment liposomes, multi-compartment liposomes, and multi-phase liposomes, depending on the type of structure. In 1965, Banghan et al. First made liposomes by suspending phospholipids in water. 1969 Huang application of ultrasound lipids