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急性胰腺炎(acute pancreatitis,AP)具有较高的发病率和病死率,15%-25%患者可进展为重症急性胰腺炎(severe acute pancreatitis,SAP),多伴发急性呼吸窘迫综合征(acute respiratory distress syndrome,ARDS)、全身炎症反应综合征(systemic inflammatory response syndrome,SIRS)和多器官功能衰竭(multiple organ dysfunction syndrome,MODS)等严