论文部分内容阅读
目的:探讨当前临床抗菌药物的应用现状,分析主要致病菌,同时进行耐药性分析,为以后的临床合理用药提供依据。方法:对于2008年6月-2011年12月在我院住院治疗的1000例患者的临床资料进行回顾性分析,总结当前临床上主要的抗菌药物。结果:在1000例患者中,有768例使用了抗菌药物,使用率为76.8%,主要用于预防用药,其中,单一用药312例,占31.2%,联合用药456例,占45.6%;对我院的临床抗菌药进行分析,其中,头孢菌素类及喹诺酮类药物应用较多,占据主导地位,而四环素类及氨基糖苷类药物应用较少;药物的使用频率(DDDs)和利用指数(DUI)从高到低依次为第三代头孢菌素类和喹诺酮类药物。结论:我院抗菌药物的管理应用较为规范,近年来有了很大的改进,但仍然存在一些问题,临床上应该加强抗菌药物的合理应用和管理。
Objective: To explore the current status of clinical application of antibacterial drugs, analysis of major pathogens, resistance analysis at the same time, to provide the basis for clinical rational drug use. Methods: The clinical data of 1000 patients hospitalized in our hospital from June 2008 to December 2011 were analyzed retrospectively to summarize the current clinical major antimicrobial agents. RESULTS: Of the 1000 patients, 768 were antibacterials, with a usage rate of 76.8%, primarily for prophylaxis, 312 of which were single-use (31.2%) and 456 (45.6%), Among them, cephalosporins and quinolones were widely used and dominated, while tetracyclines and aminoglycosides were used less frequently; DDDs and utilization index (DUI) ) From the highest to the lowest for the third generation cephalosporins and quinolones. Conclusion: The management and application of antibacterials in our hospital are more standardized and have been greatly improved in recent years. However, there are still some problems. The rational application and management of antibacterials should be strengthened clinically.