目的探讨机械通气的作用及应用体会。方法对30例重度有机磷中毒致呼吸衰竭应用机械通气治疗的患者进行回顾分析和总结。结果在综合治疗的基础上联合机械通气,获得较高的治愈率,具有良好效果。结论早期应用机械通气,选择合适的呼吸模式、恰当的参数,加强气道护理,积极预防机械通气并发症是抢救重度有机磷中毒致呼吸衰竭成功的关键。 Objective To explore the role of mechanical ventilation and its application. Methods Thirty patients with respiratory failure due to severe organophosphate poisoning were retrospectively analyzed and summarized. Results Based on the combined treatment of mechanical ventilation, access to a higher cure rate, with good results. Conclusion The early application of mechanical ventilation, select the appropriate breathing patterns, the appropriate parameters, strengthen airway care, and active prevention of complications of mechanical ventilation is the key to the successful rescue of respiratory failure caused by severe organophosphate poisoning.