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天门县地处湖北省江汉平原,人口137万余。1980年1月至1982年9月共出生婴儿71,864人,发生先天性巨结肠症17例,发病率为2.37/万。本次调查共计90例,包括天门县46例,武汉市44例。结果表明:先天性巨结肠症与农药投放量、母亲孕前期孕期接触农药,第一胎母亲年龄、胎次、产程、胎儿体重等因素均无明显相关。对母亲妊娠前半年的病史、月经史、有无饮酒、外伤、精神创伤等因素配对调查结果,发现先天性巨结肠症与母亲
Tianmen County is located in Jianghan Plain in Hubei Province, population 1370000. Between January 1980 and September 1982, 71,864 babies were born, and 17 cases of Hirschsprung’s disease occurred, with a prevalence of 2.37 per 10,000. The survey totaled 90 cases, including 46 cases of Tianmen County, Wuhan City, 44 cases. The results showed that there was no significant correlation between Hirschsprung disease and dosage of pesticide, mother ’s exposure to pesticide during the first trimester of pregnancy, age of first - born fetus, parity, birth process and fetal body weight. On the mother’s first half of pregnancy history, history of menstruation, with or without drinking, trauma, trauma and other factors paired survey findings found that Hirschsprung’s disease and mother