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众所周知强心甙具有强心效应,对充血性心力衰竭疗效显著,但也是最有毒性的药物之一。给洋地黄化病人进行麻醉,可能并不存在什么特殊问题。病人如果已发生中毒则情况因人而异,而且术中、术后还有许多因素可能加重这一危及生命的并发症,如体液、电解质和酸硷平衡失调、低氧血症,肾功能不全以及药物相互作用等。本文着重讨论与洋地黄中毒有关的麻醉问题。洋地黄对正常或衰竭的心脏都有正性肌力作用,虽然较大剂量时会产生心脏毒性,但并不影响收缩力。血清中其治疗浓度和中
It is well known that cardiac glycosides have a cardiac effect and have a significant therapeutic effect on congestive heart failure but are also one of the most toxic drugs. There may not be any special problems with anesthesia for digitalis. If the patient has been poisoned the situation varies from person to person, but also during and after surgery, there are many factors that may aggravate this life-threatening complications, such as body fluids, electrolytes and acid-base balance disorders, hypoxemia, renal insufficiency As well as drug interactions. This article focuses on the anesthetic issues associated with digitalis poisoning. Digitalis has a positive inotropic effect on normal or failing hearts, although at higher doses it produces cardiotoxicity but does not affect contractility. Serum in the treatment of its concentration and in