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目的:探讨重度酒精中毒患者的代谢紊乱特点和有效治疗。方法:总结62例重度酒精中毒患者的意识状态与血压变化,血钾、钠、氯、CO2CP、pH、RBC、血糖、尿酮体的指标变化及治疗后的效果观察。结果:62例中低血压发生率69.3%,其中昏迷组高达92.5%;昏迷组低钠、低钾、低氯合并酸中毒、高血糖、酮尿症的发生率明显高于昏睡组。治疗后6h临床症状恢复,各种检验指标>90%。结论:重度酒精中毒时,存在低血容量、低钾、低钠、低氯、酸中毒和糖代谢异常,洗胃加盐酸纳洛酮加极化液治疗有确切疗效。
Objective: To investigate the characteristics and effective treatment of metabolic disorders in patients with severe alcoholism. Methods: The state of consciousness and blood pressure in 62 patients with severe alcoholism were summarized. The changes of serum potassium, sodium, chloride, CO2-CP, pH, RBC, blood glucose and urine ketone bodies and the therapeutic effect were observed. Results: The incidence of hypotension in 62 cases was 69.3%, of which 92.5% was in coma. The incidences of hyponatremia, hypokalemia, hypochlorocholic acidosis, hyperglycemia and ketorrhea in coma were significantly higher than those in drowsiness group. After 6h clinical symptoms recovered, various test indicators> 90%. Conclusion: Severe alcoholism, there is hypovolemia, hypokalemia, hyponatremia, hypochlorosis, acidosis and abnormal glucose metabolism, gastric lavage plus naloxone hydrochloride plus polarization solution has the exact effect.