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目的探讨盐酸米诺环素软膏治疗牙周炎患者的临床疗效。方法选取2013年10月至2015年6月于辽阳市第八人民医院接受治疗的120例牙周炎患者作为研究对象,根据随机对照、平行、单盲原则将其分为对照组60例(76颗患牙)和观察组60例(75颗患牙)。对照组患者在常规治疗基础上使用碘甘油,观察组患者则在常规治疗基础上联合使用盐酸米诺环素软膏,比较两组患者临床疗效、牙周袋探诊深度、附着丧失水平、出血指数。结果观察组患者治疗的总有效率明显高于对照组,牙周袋探诊深度、附着丧失水平及出血指数均显著低于对照组,差异均有统计学意义(均P<0.05)。结论采用盐酸米诺环素软膏治疗牙周炎临床疗效显著,可有效改善患者临床症状。
Objective To investigate the clinical efficacy of minocycline hydrochloride ointment in the treatment of patients with periodontitis. Methods A total of 120 patients with periodontitis admitted to the Eighth People’s Hospital of Liaoyang City from October 2013 to June 2015 were selected and divided into control group (60 cases, 76 cases) according to randomized controlled, parallel and single-blind principle Teeth) and observation group 60 cases (75 teeth). Patients in the control group received iodine glycerol on the basis of routine treatment. Patients in the observation group received minocycline hydrochloride ointment on the basis of routine treatment. The clinical efficacy, depth of probing, attachment loss, hemorrhage index . Results The total effective rate of observation group was significantly higher than that of control group. The exploration depth, attachment loss and hemorrhage index of periodontal pocket were significantly lower than those of control group (all P <0.05). Conclusion The clinical efficacy of minocycline hydrochloride ointment in the treatment of periodontitis is significant, which can effectively improve the clinical symptoms of patients.