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目的 本文从病理角度在细胞水平上观察槐耳清膏的防癌与抑癌作用。方法 联合应用二乙基亚硝胺(DENA)、四氯化碳复制鼠肝硬化肝癌模型,分为7组,在不同阶段灌服槐耳清膏进行干预癌形成,20周后处死鼠,进行病理观察。结果 灌服槐耳清膏减缓鼠体重的下降,减轻癌变的病理变化,癌变率显著降低。槐耳也能通过抑制肝硬化干预癌的形成,其疗程与疗效呈显著正相关。结论 在鼠肝癌模型制备中灌服槐耳清膏具有确切的防癌抑癌作用,槐耳清膏是临床抗肿瘤的理想药物,将成为肿瘤综合治疗及单独治疗的主干药物。
Objective To observe the anti-cancer and anti-cancer effects of Yu Er Qing Ointment at the cellular level from the pathological perspective. Methods Rat liver cirrhosis liver cancer models were established by combining diethylnitrosamine (DENA) and carbon tetrachloride (CTC). The rats were divided into 7 groups. Carryover cream was administered at different stages to interfere with carcinogenesis. Rats were sacrificed 20 weeks later. Pathological observation. RESULTS: Gavage decoction can relieve the decrease of body weight, reduce the pathological changes of carcinogenesis, and reduce the canceration rate significantly. Auricularia can also inhibit the formation of cancer by inhibiting cirrhosis, and its course of treatment is significantly positively correlated with the therapeutic effect. Conclusion In the preparation of murine hepatocarcinoma model, it is necessary to infuse Guerchiqing ointment with the exact anti-cancer and anti-cancer effects. Yuyinqing ointment is an ideal anti-tumor drug and will become the main drug for comprehensive tumor treatment and treatment alone.