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洋葱伯克霍尔德菌(Burkholderia cepacia,BC)是近年来院内感染的几种重要条件致病菌之一,通常对健康人体并不致病,多侵袭免疫力低下的个体,常定植于囊性纤维化(CF)和慢性肉芽肿患者的肺部,是CF患者的高毒力、高致死性病原菌。该菌临床分离率不断增加,且对多种抗生素具有较高的耐药性,临床相关感染治疗困难。本文主要就BC医院感染特点、耐药性及治疗现状作一简要综述。
Burkholderia cepacia (BC) is one of several important opportunistic pathogens in nosocomial infections in recent years. Usually, it does not cause disease to the healthy human body, and many individuals with low invasive immunity often colonize the capsule The lungs of patients with fibrosis (CF) and chronic granulomatosis are highly virulent and highly lethal pathogens in CF patients. The clinical isolates of the bacteria continue to increase, and a variety of antibiotics with high resistance, clinical treatment of infection-related difficulties. This article mainly on BC hospital infection characteristics, drug resistance and treatment status for a brief review.