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1 病历摘要患者女,28岁。胸部丘疹5个月,于2014年1月8日来北京大学深圳医院就诊。患者5个月前无明显诱因于胸部出现一丘疹,逐渐变大,轻压痛,无明显瘙痒。未诊治。患者平素体健,无外伤史,家族中无类似疾病患者。体格检查:系统检查无异常。皮肤科检查:胸部近右乳下可见一枚约1.1 cm×0.8 cm结节,呈红褐色,中央轻度凹陷,边界清楚(图1A),质硬,与周围组织无粘连。皮损组织病理检查:胞质嗜酸性颗粒状的细胞呈巢索状排列,在真皮内浸润性生长,无明显异形性(图1B)。免疫组化:S-100蛋白(+)(图1C),CD68(+)(图1D),神经烯醇化酶(NSE)
A medical record Summary Female patient, 28 years old. Chest pimple 5 months, on January 8, 2014 to Peking University Shenzhen Hospital. Patient 5 months ago no obvious incentive to a pimple in the chest, gradually larger, mild tenderness, no significant itching. Not diagnosed. Patients usually healthy, no history of trauma, no similar disease in the family. Physical examination: No abnormalities in the system examination. Dermatology examination: A nearly 1.1 cm × 0.8 cm nodule was observed near the right chest of the chest, showing a reddish brown color with a slight central depression and a clear boundary (Figure 1A). It was hard and had no adhesions to the surrounding tissues. Histopathological examination of skin lesions: Cytoplasmic eosinophilic granulosa cells arranged in a nest-like manner, invasive growth in the dermis, no significant atypia (Figure 1B). Immunohistochemistry: S-100 protein (+) (Figure 1C), CD68 (+) (Figure ID), neuroenoenolase (NSE)