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目的观察栀芩桔梗方对社区获得性肺炎(CAP)患者TNF-α、IL-6、hs-CRP、PCT的影响。方法将120例痰热郁肺型CAP患者随机分为观察组和对照组。对照组采用莫西沙星注射液0.4g静脉滴注,每天1次。观察组在对照组治疗基础上加用栀芩桔梗方治疗。疗程均为14d。结果治疗前,2组患者血清TNF-α、IL-6、hs-CRP、PCT水平差异均无统计学意义(P>0.05);治疗后,2组患者TNF-α、IL-6、hs-CRP、PCT水平均较治疗前降低,且观察组治疗前后差值(下降值)较对照组有显著性差异(P<0.01)。结论栀芩桔梗方在CAP的治疗中具有抑制炎性反应和抗感染的作用。
Objective To observe the effects of Qinqin Campan recipe on TNF-α, IL-6, hs-CRP and PCT in patients with community-acquired pneumonia (CAP). Methods A total of 120 patients with phlegm and phlegm lung type CAP were randomly divided into observation group and control group. The control group with moxifloxacin 0.4g intravenous injection, 1 day. Observation group in the control group based on the treatment plus Qincui Campanulaceae treatment. Treatment are 14d. Results Before treatment, the levels of TNF-α, IL-6, hs-CRP and PCT in two groups had no significant difference (P> 0.05) CRP, PCT levels were lower than before treatment, and the difference between the observation group before and after treatment (down) was significantly different (P <0.01). Conclusion Decoction of Qinqin Campanulaceae can inhibit the inflammatory reaction and anti-infection in the treatment of CAP.