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实验采用结扎大鼠双侧颈总动脉３０ｍｉｎ后灌注６０ｍｉｎ，复制脑缺血再灌注损伤模型。通过测定缺血及再灌注后海马组织中脂质过氧化物（ＬＰＯ）含量、总抗氧化活性（ＧＡＯ）和Ｃａ２＋－ＡＴＰ酶活性，观察了葛花露和茶多酚对大鼠脑缺血再灌注损伤的影响。实验结果表明，葛花露和茶多酚能明显降低脑缺血再灌注后海马组织中ＬＰＯ含量（Ｐ＜０．０１）及保护ＧＡＯ和Ｃａ２＋－ＡＴＰ酶活性（Ｐ＜０．０１）。提示葛花露和茶多酚对脑缺血再灌注损伤具有保护作用。
In the experiment, bilateral common carotid arteries were ligated for 30 minutes and perfused for 60 minutes, and the model of cerebral ischemia-reperfusion injury was reproduced. The content of lipid peroxide (LPO), total antioxidant activity (GAO) and Ca2 + -ATPase activity in hippocampus of rats after ischemia and reperfusion were measured. The effects of Pueraria lobata and tea polyphenols on cerebral ischemia Effect of reperfusion injury. The experimental results show that Gehua Lu and tea polyphenols can significantly reduce the content of LPO (P <0.01) and protect the activities of GAO and Ca2 + -ATPase in hippocampus after cerebral ischemia-reperfusion (P <0.01). Tip Gehua Lu and tea polyphenols on cerebral ischemia-reperfusion injury has a protective effect.