胃癌是消化道最常见的恶性肿瘤之一,发病率和死亡率均较高,复发和转移是导致胃癌治疗效果差的主要原因。miR-210是近年研究较为活跃的细胞调控因子,在胃癌的发生、发展尤其是侵袭转移方面发挥了重要作用。研究表明,miR-210可通过多种途径诱导胃癌细胞发生上皮间质转化,导致胃癌复发和转移。本文就miR-210在胃癌中的研究进展作一综述。 Gastric cancer is one of the most common malignancies in the digestive tract, with high morbidity and mortality, and recurrence and metastasis are the main reasons leading to poor treatment of gastric cancer. miR-210 is a cell regulatory factor that has been actively studied in recent years. It plays an important role in the occurrence and development of gastric cancer, especially invasion and metastasis. Studies have shown that miR-210 can induce epithelial-mesenchymal transition in gastric cancer cells through multiple pathways, resulting in recurrence and metastasis of gastric cancer. This article reviews the progress of miR-210 in gastric cancer.