用离体家兔心脏灌流、小鼠常压耐缺氧和自发活动法观察熊胆对离体家兔心脏和小鼠常压耐缺氧及自主活动的影响。结果表明熊胆对离休家兔心脏冠脉流量、心肌收缩力、心率无明显影响，但可明显延长小鼠的常压耐缺氧存活时间，对照组为３０．６６±３．３８ｍｉｎ，药物组为４１．４５±５．５７ｍｉｎ，４６．６４±６．７８ｍｉｎ，小鼠的自发活动减少，并有明显的耐低温作用。 The effects of bear bile on isolated rabbit hearts and mice under normal pressure and tolerance to hypoxia and autonomic activities were observed with isolated rabbit heart perfusion, mouse hypoxia tolerance and spontaneous activity. The results showed that bear gall had no significant effect on coronary flow, myocardial contractility, and heart rate in resuscitation rabbit hearts, but it could significantly prolong the duration of normoxic hypoxia tolerance in mice. The control group was 30.66±3.38 min. For 41.45±5.57 min and 46.64±6.78 min, the spontaneous activity of the mice was reduced, and there was obvious hypothermia resistance.