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中枢神经系统内的儿茶酚胺在垂体促性腺激素分泌的神经调节中是重要的,已验明脑内单胺能通路的定位及其末梢在下丘脑的分布,有人提出在黄体生成素(LH)分泌及排卵的控制中,中枢去甲肾上腺素能神经元具有调制作用.对于去卵巢并经甾体激素预处理的大鼠,或处于动情间期(dioestrus Ⅱ)和前期(pro-oestrus)的大鼠,去甲肾上腺素(NE)可兴奋LH分泌,这似经α-肾上腺素能受体介导.但也有人提出激活中枢去甲肾上腺
Catecholamines in the central nervous system are important in the neuromodulation of pituitary gonadotropin secretion. The localization of monoaminergic pathways in the brain and the distribution of their terminals in the hypothalamus have been demonstrated. It has been suggested that in the secretion of luteinizing hormone (LH) and In the control of ovulation, central noradrenergic neurons have a modulatory effect on ovariectomized and steroid-pretreated rats, or rats in dioestrus II and pro-oestrus , Norepinephrine (NE) excitates LH secretion, which appears to be mediated by alpha-adrenergic receptors, but others have suggested activating the central noradrenal