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目的观察地塞米松联合氨溴索治疗早产儿支气管肺发育不良的临床效果。方法选取医院收治的合并支气管肺发育不良的早产儿84例,随机分为对照组和观察组,每组42例。对照组给予常规处理,观察组给予地塞米松联合氨溴索治疗,比较2组患儿吸氧时间、机械通气时间和临床效果差异。结果观察组吸氧时间和机械通气时间均明显少于对照组(P<0.01)。观察组治疗后总有效率为90.48%,高于对照组的61.90%(P<0.05)。结论地塞米松联合氨溴索治疗早产儿支气管肺发育不良临床效果显著,值得临床推广应用。
Objective To observe the clinical effect of dexamethasone combined with ambroxol on bronchopulmonary dysplasia in premature infants. Methods 84 cases of premature infants with bronchopulmonary dysplasia admitted to hospital were randomly divided into control group and observation group, with 42 cases in each group. The control group was given conventional treatment. The observation group was treated with dexamethasone and ambroxol. The oxygen inhalation time, mechanical ventilation time and clinical effect were compared between the two groups. Results Oxygen inhalation time and mechanical ventilation time in the observation group were significantly less than those in the control group (P <0.01). The total effective rate of the observation group after treatment was 90.48%, which was 61.90% higher than that of the control group (P <0.05). Conclusion Dexamethasone combined with ambroxol treatment of bronchopulmonary dysplasia in preterm children with significant clinical effect, it is worthy of clinical application.