西红花总苷的药理学研究Ⅰ.对炎症及免疫功能的影响

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西红花总苷ig明显抑制二甲苯所致小鼠急性耳廓肿胀、醋酸所致小鼠腹腔毛细血管通透性增高及蛋清、角叉菜胶所致大鼠足跖肿胀,且有一定的镇痛效应。对正常小鼠的免疫器官重量、非特异性免疫、特异性体液免疫功能无明显影响,但对迟发型变态反应有明显的抑制作用。 Saffron ig significantly inhibited xylene-induced acute ear swelling in mice, acetic acid-induced increase in capillary permeability in the abdominal cavity of the mice, and swelling of the paws in rats caused by egg white and carrageenan. Analgesic effect. There was no significant effect on the weight of immune organs, non-specific immunity, specific humoral immune function in normal mice, but it had a significant inhibitory effect on late-type allergic reactions.
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