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目的探讨卵巢癌组织HSPTO的表达及HSP70与组织类型 ,组织分级 ,患者年龄之间的关系。方法应用免疫组化SP法分别检测 4 2例卵巢癌组织中HSP70的表达。结果卵巢癌中HSP70阳性率高于正常组织 ,而且HSP70在低分化卵巢癌中的阳性率高于高分化癌。结论说明HSP70的过度表达可能与卵巢癌的发生、发展以及预后有关
Objective To investigate the expression of HSPTO and the relationship between HSP70 and tissue type, histological grade and patient’s age in ovarian cancer. Methods Immunohistochemical SP method were used to detect the expression of HSP70 in 42 cases of ovarian cancer. Results The positive rate of HSP70 in ovarian cancer was higher than that in normal tissues, and the positive rate of HSP70 in poorly differentiated ovarian cancer was higher than that in well-differentiated cancer. Conclusions The overexpression of HSP70 may be related to the occurrence, development and prognosis of ovarian cancer