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目的讨论氨苄青霉素在治疗淋菌性外阴炎的疗效与安全性。方法选择2010年6月——2012年6月间,患淋菌性外阴炎的患者50例,随机分为两组,包括治疗组和对照组各25例,治疗组采用氨苄青霉素治疗,对照组采用红霉素治疗,治疗1个月后,比较两组患者的疗效和安全性。结果治疗组患者显效14例,有效5例,无效6例,总有效率为,对照组患者显效8例,有效8例,无效9例,总有效率为,两组差异显著,p<0.05,具有统计学意义;治疗组患者发生皮疹3例,胃肠道反应2例,头晕头痛2例,不良反应率为,对照组患者发生皮疹5例,胃肠道反应4例,头晕头痛1例,不良反应率为,两组差异显著,p<0.05,具有统计学意义。结论临床应用氨苄青霉素治疗淋菌性外阴炎,性能安全可靠,可以应用。
Objective To discuss the efficacy and safety of ampicillin in the treatment of gonococcal vulvitis. Methods From June 2010 to June 2012, 50 patients with gonococcal vulvitis were randomly divided into two groups, including 25 cases in the treatment group and the control group. The treatment group was treated with ampicillin and the control group Erythromycin treatment, 1 month after treatment, the efficacy and safety of the two groups were compared. Results In the treatment group, 14 cases were markedly effective, 5 cases were effective and 6 cases were ineffective. The total effective rate was 8 cases in the control group, 8 cases were effective and 9 cases were ineffective. The total effective rate was significant difference between the two groups (p <0.05) The patients in the treatment group had rash in 3 cases, gastrointestinal reaction in 2 cases and dizziness and headache in 2 cases. The adverse reaction rate was 5 cases in the control group with rash, 4 cases with gastrointestinal reaction, 1 case with dizziness and headache, The adverse reaction rate was significant difference between the two groups, p <0.05, with statistical significance. Conclusion Clinical application of ampicillin in the treatment of gonococcal vulvitis, safe and reliable performance, can be applied.