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Objective: To evaluate Tpeak- Tend ( Tp- e) interval in surface standard ECG as a new risk factor for arrhythmic event inpatient with Brugada syndrome. Methods: 23 male patients with Brugada syndrome and 20 male patients with paroxysmalsupraventricular tachycardia ( PSVT) as the control group were investigated in this study. Tp- e interval in surface standardECG was compared between BrS and PSVT patients. Results: Tp- e interval in BrS patients was significantly longer thanthat in PSVT patients ( 109.57±22.86 ms vs. 88.50±13.08ms, P<0.05) . There was significant difference in Tp- e interval be-tween 16 BrS patients with arrhythmic events ( including syncope, clinical ventricular fibrillation [ VF] and programmed elec-trical stimulation [ PES] - induced VF) and 7 BrS patients without arrhythmic events and PSVT patients ( 118.12±20.40ms vs.90.00±15.27ms, P<0.05; 118.12±20.40ms vs. 88.50±13.08ms, P<0.05). However, Tp- e interval was similar in BrS patients with-out arrhythmic events and PSVT patients (90.00±15.27ms vs 88.50±13.08ms, P>0.05). Conclusion: The prolongation of Tp- einterval could serve as a new noninvasive event predictor for arrhythmic events in patients with Brugada syndrome.
Methods: 23 male patients with Brugada syndrome and 20 male patients with paroxysmal supraventricular tachycardia (PSVT) as the Tp-e interval in BrS patients was significantly longer thanthat in PSVT patients (109.57 ± 22.86 ms vs. 88.50 ± 13.08 ms , There was significant difference in Tp-e interval be-tween 16 BrS patients with arrhythmic events (including syncope, clinical ventricular fibrillation [VF] and programmed elec-trical stimulation [PES] -induced VF) and 7 BrS Patients without arrhythmic events and PSVT patients (118.12 ± 20.40ms vs.90.00 ± 15.27ms, P <0.05; 118.12 ± 20.40ms vs. 88.50 ± 13.08ms, P <0.05). However, Tp-e interval was similar in BrS patients with-out arrhythmic events and PSVT patients (90.00 ± 15.27 ms vs 88.50 ± 13.08 ms, P> 0.05). Conclusion: The prolongation of Tp-einterval could serve as a new noninvasive event predictor for arrhythmic events in patients with Brugada syndrome.