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目的探讨维库溴铵治疗硫丹中毒所致剧烈抽搐的疗效。方法 13例硫丹中毒患者均出现全身频繁持续性抽搐,常规给予安定、苯巴比妥,如不能控制发作,静脉给予维库溴铵4 mg,继以1~2mg/h速度持续静脉泵注,并常规给予洗胃、综合及对症支持治疗。结果给予维库溴铵后,5例于40min内抽搐得到有效控制,其余8例于2~5 h内抽搐基本被控制;维库溴铵维持时间2 d~1周;平均机械通气时间3 d;本组无死亡病例。结论维库溴铵可有效控制硫丹中毒所致的顽固性抽搐,提高抢救成功率。
Objective To investigate the efficacy of vecuronium in the treatment of severe convulsions caused by endosulfan poisoning. Methods Thirteen cases of endosulfan poisoning patients with frequent persistent convulsions, routinely given diazepam, phenobarbital, if not controlled seizures, intravenous vecuronium 4 mg, followed by continuous intravenous infusion of 1 ~ 2mg / h speed , And routine gastric lavage, comprehensive and symptomatic supportive treatment. Results After intravenous vecuronium, 5 cases were effectively controlled within 40 minutes of convulsion, and the remaining 8 cases were basically controlled within 2 to 5 hours. Vecuronium maintained for 2 days to 1 week. Mean mechanical ventilation time was 3 days There were no deaths in this group. Conclusion Vecuronium can effectively control refractory convulsions caused by endosulfan poisoning and improve the success rate of rescue.