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目的:探讨垂体后叶素联合卡前列素氨丁三醇治疗胎盘早剥产后大出血的效果。方法:选取该院2011年12月~2013年12月收治的85例胎盘早剥产后大出血患者为研究对象,根据随机数字表将患者分为观察组43例以及对照组42例,对照组孕妇给予前列素氨丁三醇治疗,观察组在对照组的基础上在胎儿、胎盘娩出后于子宫肌层注射垂体后叶素,观察两组患者止血时间、第三产程、产后出血发生率、产后15 min、产后30 min、产后2 h、产后24 h出血量及总出血量,比较两组患者产后输血、子宫切除、胎儿窒息、胎儿死亡的发生率。结果:观察组止血时间、第三产程时间显著短于对照组,差异有统计学意义(P<0.05)。观察组产后15 min、产后30 min、产后2 h、产后24 h出血量少于对照组,差异有统计学意义(P<0.05)。观察组产后出血率、输血率、子宫切除率、胎儿窒息率、胎儿死亡率低于对照组,差异有统计学意义(P<0.05)。结论:垂体后叶素对胎盘早剥产后出血治疗效果显著,可有效预防产后出血,降低产后出血发生率,减少不良妊娠结局的发生,有利于患者预后。
Objective: To investigate the effect of pituitrin combined with carboprost trometamol on postpartum hemorrhage after placental abruption. Methods: Eighty-five patients with postpartum hemorrhage after placental abruption were selected from December 2011 to December 2013 in our hospital. According to the random number table, the patients were divided into observation group (n = 43) and control group (n = 42) Prostaglandin trometamol treatment, the observation group in the control group based on the fetus, placenta after delivery in the myometrium pituitrin injection to observe the two groups of patients bleeding time, the third stage of labor, the incidence of postpartum hemorrhage, postpartum 15 min, 30 min postpartum, 2 h postpartum, 24 h postpartum hemorrhage and total blood loss. The incidence of postpartum blood transfusions, hysterectomy, fetal asphyxia and fetal death were compared between the two groups. Results: The bleeding time and the third stage of labor in the observation group were significantly shorter than those in the control group (P <0.05). The observation group 15 min postpartum, 30 min postpartum, 2 h postpartum, 24 h postpartum blood loss less than the control group, the difference was statistically significant (P <0.05). The postpartum hemorrhage rate, blood transfusion rate, hysterectomy rate, fetal asphyxia rate and fetal mortality rate in the observation group were lower than those in the control group (P <0.05). Conclusion: Pituitrin has a significant therapeutic effect on postpartum hemorrhage after placental abruption, which can effectively prevent postpartum hemorrhage, reduce the incidence of postpartum hemorrhage and reduce the incidence of adverse pregnancy outcomes, which is in favor of prognosis.