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作者通过静脉给药探测￣３Ｈ－天麻甙元和￣３Ｈ－天麻素在小鼠体内的分布，并采用硅胶薄板层析法对注射￣３Ｈ－天麻素的小鼠组织提取液的放射性成份进行分析，研究了二者在小鼠体内的分布和代谢过程。结果显示：天麻素（Ｇａｓｔｒｏｄｉｎ）可以透过血脑屏障进入脑内，并在脑、血及肝中迅速分解为天麻甙元（Ｇａｓｔｒｏｄｉｇｅｎｉｎ），然后以天麻甙元的形式存留在脑组织内，发挥中枢镇静作用。天麻甙元和天麻素都主要经肾脏排泄，天麻素在小鼠体内可能存在肠肝循环。
The authors detected the distribution of ~3H-Gastrodia aglycone and 3H-gastrodin in mice by intravenous administration and the radioactive components of mouse tissue extracts injected with 3H-gastrodin were analyzed by silica gel thin-layer chromatography , The distribution and metabolism of the two in mice were studied. The results showed that Gastrodin can penetrate the blood-brain barrier into the brain and rapidly decompose into gastrodigenin in the brain, blood and liver, and then stay in brain tissue in the form of gastrodin. Central sedative effect. Gastrodia aglycone and gastrodin are mainly excreted by the kidneys, gastrodin may exist in mice intestinal enterohepatic circulation.