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目的了解立止血在预防和治疗心胸外科手术后出血的效果。方法５５９例心胸外科手术病人随机分两组，对照组２２７例应用止血敏、止血芳酸和安络血；实验组３３２例应用立止血，分别在手术后开始预防性用药，观察术后第１，２，３天及总的出血量。５６例术后已有明显出血病人随机分为两组，对照组２２例联合应用冷沉淀，实验组３４例联合应用立止血进行止血。观察用药后２４小时出血量，同时观察血压、心率（律）、呼吸及全身情况。结果预防性用立止血组术后第１，２，３天及总的出血量明显少于对照组；治疗术后出血联台应用立止血组２４小时后出血量明显低于对照组。用立止血前后血压、心率、呼吸未见异常改变，亦未见过敏及血栓栓塞并发症。结论在心胸外科术后可选用立止血预防和治疗出血，无明显副作用。
Objective To understand the effect of hemostasis on the prevention and treatment of bleeding after thoracic surgery. Methods A total of 559 patients undergoing cardiothoracic surgery were randomly divided into two groups. 227 cases in the control group received hemostatic and anticonvulsant antithrombotic drugs, and 332 cases in the experimental group received antithrombotic therapy. Prophylactic medication was started after the operation. The first , 2,3 days and the total amount of bleeding. Fifty-six patients with obvious hemorrhage after operation were randomly divided into two groups. In the control group, 22 cases were treated with cryoprecipitation. In the experimental group, 34 cases were treated with antithrombotic hemostasis. Observe the amount of bleeding 24 hours after treatment, while observing blood pressure, heart rate (law), breathing and general condition. The results of prophylactic use of anti-hemostatic group 1, 2, 3 days after surgery and the total amount of bleeding was significantly less than the control group; treatment of bleeding combined with anti-hemostatic group 24 hours after bleeding was significantly lower than the control group. Before and after standing with blood pressure, heart rate, no abnormal changes in breathing, no allergies and thromboembolism complications. Conclusion In patients with cardiothoracic surgery, hemostasis can be used to prevent and treat bleeding without obvious side effects.