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目的:探讨苯妥英钠联合川芎嗪注射液治疗外伤性癫痫的临床疗效。方法:98例外伤性癫痫患者随机分为治疗组与对照组各49例,对照组予苯妥英钠治疗,治疗组在对照组的基础上加用川芎嗪针治疗,比较两组疗效。结果:治疗组总有效率为98.0%,高于对照组的79.6%(P<0.05);两组治疗后癫痫发作次数均较治疗前减少,发作持续时间均缩短,治疗组显著低于对照组(P<0.05);治疗组脑电图复常率为82.2%,高于对照组的44.9%(P<0.05)。结论:苯妥英钠联合川芎嗪注射液治疗外伤性癫痫可显著改善患者的临床症状,促进患者神经功能的康复。
Objective: To investigate the clinical efficacy of phenytoin combined with ligustrazine in the treatment of traumatic epilepsy. Methods: A total of 98 patients with traumatic epilepsy were randomly divided into treatment group and control group, 49 cases in each group. The control group was treated with phenytoin sodium. The treatment group was treated with ligustrazine on the basis of the control group. The curative effect was compared between the two groups. Results: The total effective rate of the treatment group was 98.0%, which was higher than that of the control group (79.6%, P <0.05). The number of seizures decreased after treatment in both groups and the duration of the episodes were shortened, the treatment group was significantly lower than the control group (P <0.05). The recovery rate of electroencephalogram in treatment group was 82.2%, which was higher than that in control group (44.9%, P <0.05). Conclusion: Treating traumatic epilepsy with phenytoin and ligustrazine can significantly improve the clinical symptoms and promote the recovery of neurological function.