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近几年来,由于免疫学的飞速发展,白血病与体液免疫的关系,受到许多学者的关注。我院于1979年应用免疫球蛋白(IgG、IgA、IgM),对38例急性粒细胞型白血病,急性淋巴细胞型白血病进行了体液免疫功能的初步观察,总结如下: (一)材料与方法: 1)、所用免疫球蛋白板Ig(G、A、M)系北京生物制品研究所供应。批号79—5。 2)、方法按供应单位说明使用。正常值:对50例正常献血员进行了免疫球蛋白G、A、M检测,其值为: IgG:11.6—14.6mg/ml平均值:13.1±1.6mg/ml(毫克/毫升) IgA:1.7—3.9mg/ml平均值:2.79±1.08mg/ml(毫克/毫升)。 IgM:0.86～1.5mg/ml平均值:1.18±0.32mg/ml(毫克/毫升)。 (二)检测对象和结果: 在检测的38例临床标本中,急性淋巴细胞型白血病20例,完全缓解者5例,急性粒细胞型白血病10例、部分缓解者3例。
In recent years, due to the rapid development of immunology, the relationship between leukemia and humoral immunity has attracted the attention of many scholars. Our hospital in 1979, the application of immunoglobulin (IgG, IgA, IgM), 38 cases of acute myeloid leukemia, acute lymphoblastic leukemia humoral immune function were summarized as follows: (a) Materials and Methods: 1), the immunoglobulin Ig (G, A, M) is supplied by Beijing Institute of Biological Products. Lot number 79-5. 2), the method used by the supplier description. Normal: 50 normal blood donors were tested for immunoglobulin G, A, M values: IgG: 11.6-14.6 mg / ml Average: 13.1 ± 1.6 mg / ml IgA: 1.7 -3.9 mg / ml Average: 2.79 ± 1.08 mg / ml (mg / ml). IgM: 0.86 ~ 1.5mg / ml Average: 1.18 ± 0.32mg / ml (mg / ml). (B) test objects and results: In the 38 cases of clinical specimens tested, acute lymphoblastic leukemia in 20 cases, complete remission in 5 cases, acute myeloid leukemia in 10 cases, 3 cases of partial remission.