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目的评价PET显像与CT/MRI和临床触诊比较在舌癌颈部淋巴结转移判定中的应用价值。方法38例舌癌患者在术前两周分别进行FDGPET与CT/MRI检查,分别获取PET、CT/MRI和临床触诊的淋巴结状况并以病理结果为金标准分析三种方法在敏感性、特异性及准确率方面的差异。结果PET在判定淋巴结转移的敏感性上比CT/MRI和临床触诊分别高11.1%(83.3%vs72.2%,P=0.423)和16.6%(83.3%vs66.7%,P=0.248);特异性比CT/MRI和临床触诊分别高5%(80%vs75%,P=0.703)和15%(80%vs65%,P=0.288)。PET、CT/MRI和临床触诊的准确率分别是81.6%,73.7%和65.8%。结论PET在舌癌颈部淋巴结转移判定中的敏感性、特异性及准确率方面略好于CT/MRI和临床触诊。虽然结果无统计学上的差异,我们仍认为PET作为舌癌淋巴结转移判定中的一种辅助方法有重要的作用。
Objective To evaluate the value of PET imaging and CT / MRI and clinical palpation in judging cervical lymph node metastasis of tongue cancer. Methods Thirty-eight patients with tongue cancer were examined by FDG PET and CT / MRI two weeks before operation. The status of PET, CT / MRI and clinical palpation were obtained respectively. The pathological results were taken as gold standard to analyze the sensitivity and specificity Sex and accuracy of the differences. Results PET was 11.1% (83.3% vs 72.2%, P = 0.423) and 16.6% (83.3% vs 66.7%, P = 0.248) higher than CT / MRI and clinical palpation in determining the sensitivity of lymph node metastasis. Specificity was 5% (80% vs 75%, P = 0.703) and 15% (80% vs 65%, P = 0.288) higher than CT / MRI and clinical palpation, respectively. The accuracy rates of PET, CT / MRI and clinical palpation were 81.6%, 73.7% and 65.8% respectively. Conclusion The sensitivity, specificity and accuracy of PET in cervical lymph node metastasis of tongue cancer are slightly better than that of CT / MRI and clinical palpation. Although the results were not statistically different, we still believe that PET as an adjunct to lymph node metastasis of tongue cancer has an important role.