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目的:验证核心下尿路症状评分(Core Lower Urinary Tract Symptom Score,CLSS)在中国男性人群中的有效性。方法:随机选择2014年7月~2015年6月因下尿路症状(lower urinary tract symptom,LUTS)于我院泌尿外科初次门诊就诊或住院的730例患者作为试验组进行研究,另外选择70例非LUTS患者作为对照组。患者独立完成CLSS和国际前列腺症状评分(International Prostate Symptom Score,IPSS),分析CLSS和IPSS的相关性并比较CLSS和IPSS对患者生活质量的影响。结果:试验组CLSS中除了压力性尿失禁外,日间尿频、夜尿、尿急、尿不尽、尿踌躇、尿线细、急迫性尿失禁、膀胱痛和尿道痛的阳性率均显著高于对照组(P<0.05);Spearman等级相关检验结果显示CLSS和IPSS中重合的6个问题的评分结果及总分均存在显著相关性;回归分析表明两个问卷中重合的尿频、尿急、夜尿、尿不尽、尿踌躇,以及CLSS中的膀胱痛和尿道痛是较差生活质量的独立影响因素。结论:应用CLSS可以简单全面有效的评估男性患者的LUTS,值得在临床中推广应用。
Objective: To verify the validity of Core Lower Urinary Tract Symptom Score (CLSS) in Chinese male population. Methods: From July 2014 to June 2015, 730 patients with lower urinary tract symptoms (LUTS) who were seen or hospitalized in the first outpatient urology of our hospital were selected as the experimental group. Another 70 patients Non-LUTS patients served as control group. The patients independently completed CLSS and International Prostate Symptom Score (IPSS), analyzed the correlation between CLSS and IPSS, and compared the impact of CLSS and IPSS on the quality of life of patients. Results: In addition to stress urinary incontinence, the positive rate of urinary frequency, nocturia, urinary urgency, urinary frequency, hesitancy, urinary fineness, urge incontinence, bladder pain and urinary tract pain were all significantly higher in CLSS (P <0.05). The results of Spearman rank correlation test showed that there were significant correlations between the score and the total score of the 6 questions in CLSS and IPSS. Regression analysis showed that the coincidence of urinary frequency, urinary urgency, Nocturia, urinary exhaustion, hesitancy in urine, and bladder and urethral pain in the CLSS are independent contributors to poor quality of life. Conclusion: CLSS can be used to evaluate the LUTS of male patients simply and comprehensively, which is worth popularizing in clinic.