克山病是一种以心肌受累为主要表现的地方性疾病。虽然经过近50年研究,至今病因尚未阐明,但在60年代初期对于克山病的预防和治疗都取得了重要进展,在继大剂量维生素 C静脉注射抢救克山病心源性休克患者获得成功之后,根据克山病地区内外环境缺硒,在硒能预防动物白肌病的启发下,采用亚硒酸钠预防 Keshan disease is a kind of endemic disease which is the main manifestation of myocardial involvement. Although after nearly 50 years of research, the etiology has not been elucidated yet, in the early 1960s, important progress has been made in the prevention and treatment of Keshan disease. The success was achieved after intravenous injection of large doses of vitamin C to rescue Keshan’s cardiogenic shock After that, according to the lack of selenium inside and outside the Keshan disease, selenium can be used to prevent animal white muscle disease inspired by the use of sodium selenite prevention