1例38岁女性患者,因肺腺癌晚期食欲欠佳及恶液质状态,口服甲地孕酮分散片(宜利治)160 mg·d-1治疗。1周后,患者出现左下肢深静脉血栓,停药并启动低分子肝素、华法林抗凝治疗。14 d后,患者患肢肿胀、疼痛减轻,下肢深静脉血管部分再通,予出院后口服华法林3.75 mg·d-1继续抗凝治疗并定期监测PT-INR。 A 38-year-old female patient underwent oral administration of megestrol-treated dispersible tablets (Yilizhi) at a dose of 160 mg · d-1 due to poor late appetite and cachexia status. One week later, the patient developed deep venous thrombosis of the left lower extremity, withdrawal of medication, and initiation of low molecular weight heparin and warfarin anticoagulation. After 14 days, the patient’s limbs were swollen and the pain was relieved. The deep venous blood vessels of the lower extremities were recanalized. After discharge, warfarin 3.75 mg · d-1 was given to continue anticoagulant therapy and PT-INR was monitored regularly.