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目的:分析盐酸氨溴索雾化吸入治疗支气管扩张的临床疗效。方法:我院收治的支气管扩张确诊患者76例,随机分成治疗组和对照组。两组在接受感染控制、体位引流基础治疗的同时,治疗组患者接受盐酸氨溴索雾化吸入治疗,对照组患者接受α-糜蛋白酶氧雾化吸入治疗,分别记录两组患者肺部啰音的消失时间、全部痰液排出时间和不良反应发生的概率,在入院治疗当天和接受治疗10d后,对两种患者分别进行动脉气血分析和肺功能测定,并且结合血气分析和肺功能的改善情况,综合判断治疗效果。对两组患者接受治疗后临床表现中的全部痰液的排出时间、肺部啰音的消失时间、显效率、好转率、无效率以及总体有效率进行比较。结果:接受盐酸氨溴索雾化吸入治疗后,治疗组的肺部啰音消失时间和全部痰液排出时间明显短于对照组,两组结果存在显著差异,具有统计学意义(P<0.05);在治疗显效率、好转率以及总体有效率上,治疗组液均比对照组高,差异有显著的统计学意义(P<0.05);而在治疗无效率上,治疗组则明显低于对照组低,差异有显著的统计学意义(P<0.05)。结论:使用盐酸氨溴索氧气驱动雾化吸入辅助治疗支气管扩张的治疗方案,操作简单方便,疗效显著并且不良反应发生率小,可在临床中推广使用。
Objective: To analyze the clinical efficacy of ambroxol hydrochloride inhalation in the treatment of bronchiectasis. Methods: 76 cases of bronchiectasis diagnosed in our hospital were randomly divided into treatment group and control group. In the two groups receiving infection control, drainage and basic treatment of body position at the same time, the treatment group received inhalation of ambroxol hydrochloride inhalation, patients in the control group received α-chymotrypsin oxygen inhalation therapy were recorded in both groups of patients with pulmonary rales Disappearance of all sputum time and adverse reactions occurred in the probability of admission on the day of treatment and receiving treatment after 10d, respectively, two patients were analyzed arterial blood gas and pulmonary function tests, combined with blood gas analysis and pulmonary function improvement Situation, a comprehensive assessment of treatment. The time of sputum discharge, the time of pulmonary rales disappearing, the markedly effective rate, the improvement rate, the inefficiency rate and the overall effective rate of clinical manifestations in both groups after treatment were compared. Results: After inhalation of ambroxol hydrochloride inhalation, the pulmonary rales disappeared and the time of sputum excretion in the treatment group was significantly shorter than that of the control group. There was significant difference between the two groups (P <0.05) ; In the treatment of markedly effective rate, improvement rate and the overall effective rate, the treatment group than the control group were higher liquid, the difference was statistically significant (P <0.05), but in the treatment of inefficiency, the treatment group was significantly lower than the control Group low, the difference was statistically significant (P <0.05). Conclusion: The treatment of bronchial dilation with ambroxol hydrochloride driven aerosol inhalation is simple and convenient, the curative effect is obvious and the incidence of adverse reactions is small, so it can be widely used in clinical practice.