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目的:了解冬春季住院患儿急性下呼吸道感染(ARI)的病毒感染状况,为临床儿童急性呼吸道感染提供病毒病原学诊断依据。方法:选择2008年11月～2009年4月在九江市妇幼保健院呼吸内科住院的急性下呼吸道感染患儿,取其入院当天的静脉血,进行呼吸道病毒IgM检测,包括呼吸道合胞病毒(RSV)、腺病毒(ADV)、流感病毒(IV)、副流感病毒(PIV),并对检测标本阳性的病例进行统计分析。结果:在151例患儿送检标本中,阳性37例,占24.5%(37/151)。阳性标本中呼吸道合胞病毒32例(86.5%),腺病毒1例(2.7%),流感病毒2例(5.4%),副流感病毒2例(5.4%)。RSV的发病高峰在12月至次年的1、2月份,RSV感染多见于3岁以下儿童,发病高峰年龄为6个月以下儿童,男、女发病比例为1.9∶1。结论:九江市妇幼保健院2008年11月～2009年4月住院患儿中,引起急性下呼吸道感染的病毒病原体以RSV为主,IV和PIV次之。
Objective: To understand the infection status of acute lower respiratory tract infection (ARI) in hospitalized children in winter and spring, and to provide the basis of virus etiological diagnosis for clinical children with acute respiratory infection. Methods: Children with acute lower respiratory tract infection who were hospitalized in Respiratory Medicine Department of MCH Hospital of Jiujiang City from November 2008 to April 2009 were selected for venous blood samples on the day of hospital admission for respiratory virus IgM detection, including respiratory syncytial virus (RSV) ), Adenovirus (ADV), influenza virus (IV) and parainfluenza virus (PIV). Statistical analysis was made on the positive cases. Results: Of the 151 samples examined in children, 37 were positive, accounting for 24.5% (37/151). Positive specimens of respiratory syncytial virus in 32 cases (86.5%), adenovirus in 1 case (2.7%), influenza virus in 2 cases (5.4%), parainfluenza virus in 2 cases (5.4%). The peak incidence of RSV was between January and February of the following year in December and February. RSV infection was more common in children under 3 years old. The peak age of onset was less than 6 months. The incidence of RSV was 1.9: 1. Conclusion: Among the hospitalized children from November 2008 to April 2009 in Jiujiang MCH, the viral pathogens causing acute lower respiratory tract infection were mainly RSV, followed by IV and PIV.