脓毒症(sepsis)是由感染所致的破坏性的全身炎症反应综合征(systemic inflammatory response syndrome,SIRS)[1-4]。目前发病机制未明,其治疗也成为临床上棘手的问题。曾认为抗炎治疗是其最有效的治疗手段,但20多年的临床实践经验证明该疗法成效并不明显[3-4]。早期联合广谱抗生素的使用、及时的液体复苏等对症疗法不断发展[5],但其死 Sepsis is a destructive systemic inflammatory response syndrome (SIRS) caused by infection [1-4]. The current pathogenesis is unknown, and its treatment has also become a clinically difficult problem. Once considered anti-inflammatory treatment is the most effective treatment, but more than 20 years of clinical practice have shown that the efficacy of the treatment is not obvious [3-4]. The early use of broad-spectrum antibiotics, timely liquid resuscitation and other symptomatic therapy continue to develop [5], but its death