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目的分析影响新生儿肺出血(NPH)的高危因素。方法分析108例NPH患儿(NPH组)的临床资料,并与108例非NPH新生儿(对照组)比较。结果 NPH组中,经积极抢救治疗临床治愈44例,抢救无效而临床死亡57例,7例自动出院。性别、新生儿窒息、新生儿呼吸窘迫综合征、感染性肺炎、酸中毒、胎膜早破、先天性心脏病、新生儿休克、肺表面活性物质的应用、胎龄、出生体重两组比较有统计学差异(P<0.01或P<0.05)。胎龄33~37周、男性、感染性肺炎、新生儿窒息、新生儿呼吸窘迫综合征为NPH高危因素(P<0.01或P<0.05)。结论 NPH是严重威胁新生儿生命的危重病,主要与胎龄33~37周、男性、窒息、感染性肺炎及呼吸窘迫综合征有密切关系。
Objective To analyze the risk factors affecting neonatal pulmonary hemorrhage (NPH). Methods The clinical data of 108 children with NPH (NPH group) were analyzed and compared with 108 non-NPH newborns (control group). Results In the NPH group, 44 cases were clinically cured by active rescue treatment, 57 cases died of clinical rescue and 7 cases were discharged automatically. Gender, neonatal asphyxia, neonatal respiratory distress syndrome, infectious pneumonia, acidosis, premature rupture of membranes, congenital heart disease, neonatal shock, pulmonary surfactant application, gestational age, birth weight were compared between the two groups Statistical difference (P <0.01 or P <0.05). Male, infectious pneumonia, neonatal asphyxia and neonatal respiratory distress syndrome were the risk factors of NPH (P <0.01 or P <0.05) at gestational age from 33 to 37 weeks. Conclusion NPH is a serious disease that threatens the life of neonates. It is mainly related to 33-37 gestational age, male, asphyxia, infectious pneumonia and respiratory distress syndrome.