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目的临床观察心绞痛(AP)对随后发生急性心肌梗死(AMI)的影响及其预后。方法根据临床117例AMI患者的资料进行分析,将AMI前有无AP分为A组和B组两组,并将两者的临床指标进行比较。结果 A组(有心绞痛组)大面积心梗,CPK、CPK-MB峰值,KillipⅡ级以上心衰,梗死后心绞痛发生率,住院期间病死率均明显低于B组(无心绞痛组),P<0.05。但两者恶性心律失常发生率比较差异无统计学意义。结论 AMI前有心绞痛对AMI有一定的保护作用,体现了心肌缺血预适应(IPC),具体表现在限制心梗面积的扩大,降低AMI后心力衰竭的发生率和住院病死率。
Objective To observe the effect and prognosis of angina pectoris (AP) on subsequent acute myocardial infarction (AMI). Methods According to the clinical data of 117 patients with AMI, AM patients were divided into A group and B group before API, and the clinical indexes of the two groups were compared. Results The myocardial infarction, CPK, CPK-MB peak, KillipⅡlevel heart failure, post-infarction angina pectoris rate and hospital stay mortality in group A (angina group) were significantly lower than those in group B (no angina group), P < 0.05. However, the incidence of malignant arrhythmia between the two groups showed no significant difference. Conclusions Angina pectoris before AMI has a certain protective effect on AMI, which manifests myocardial ischemic preconditioning (IPC), which specifically limits the expansion of myocardial infarction size and reduces the incidence of heart failure and in-hospital mortality after AMI.