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目的探讨乌拉地尔治疗高血压合并急性心力衰竭的临床效果。方法选取我院收治的82例高血压合并急性心力衰竭病人为此次研究对象,随机将其分为两组,各41例。对照组给予硝酸异山梨酯注射液治疗,观察组给予乌拉地尔治疗,比较两组临床治疗的有效性及安全性。结果观察组治疗有效率为90.24%,不良反应发生率为7.32%,与对照组治疗有效率70.37%、不良反应发生率24.39%比较,差异有统计学意义(P<0.05)。治疗后观察组心率变化明显优于对照组(P<0.05)。结论乌拉地尔治疗高血压合并急性心力衰竭的安全性和有效性明显优于硝酸异山梨酯注射液,可改善病人的血压和心率。
Objective To investigate the clinical efficacy of Urapidil in the treatment of hypertension complicated with acute heart failure. Methods Eighty-two patients with hypertension and acute heart failure admitted to our hospital were randomly divided into two groups (41 in each). The control group was treated with isosorbide dinitrate injection. The observation group was treated with urapidil. The effectiveness and safety of the two groups were compared. Results The effective rate of observation group was 90.24%, the incidence of adverse reactions was 7.32%, which was significantly higher than that of control group (70.37%) and adverse reaction rate (24.39%) (P <0.05). After treatment, heart rate in observation group was significantly better than that in control group (P <0.05). Conclusion The safety and efficacy of Urapidil in the treatment of hypertension complicated with acute heart failure are significantly better than that of isosorbide dinitrate injection, which can improve the blood pressure and heart rate of patients.