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目的 分析本市不同人群SARS抗体水平,为今后防治提供依据。方法 采用酶联免疫吸附试验(ELISA)检测SARS病人、疑似、留观病人、密切接触者、医务人员和社区一般人群等血清中SARS特异性抗体并进行分析比较。结果 SARS病人抗体阳性率为87 5 0 % ,其他非SARS病人、密切接触者和社区一般人群抗体阳性率分别为0 . 5 8%、0 . 3 0 %和0 .5 4% ,输血者为0 .48%。SARS病人与非SARS病人及其他不同人群抗体阳性率差异有统计学意义,有暴露史与无暴露史人群、有外出史与无外出史人群以及各年龄组之间抗体阳性率无明显差异。结论 上海市不同人群SARS隐性感染低,其抗体可持续半年以上。低年龄组人群无感染状况值得研究。
Objective To analyze the level of SARS antibody in different population in this city and provide the basis for future prevention and treatment. Methods Serum SARS-specific antibodies against SARS patients, suspected patients, patients with close observation, close contacts, medical personnel and community general population were detected by enzyme linked immunosorbent assay (ELISA) and analyzed. Results The positive rate of antibodies in SARS patients was 87.5%. The positive rates of antibodies in SARS patients, close contacts and common people in the community were 0.58%, 0.30% and 0.54% respectively. The blood transfusion recipients were 0 .48%. There were significant differences in the positive rate of antibodies between SARS patients and non-SARS patients and other different groups. There was no significant difference in the positive rates of antibody between the out-of-history and out-of-life groups and the age groups. Conclusion In different populations in Shanghai, the latent infection of SARS is low, and the antibodies can last more than six months. Low-age group of people without infection worth studying.