作者对41例行手术治疗并随访2年以上的喉鳞癌患者用流式细胞测定法测定癌细胞核DNA量。结果:异倍体率为65.85％。异倍体肿瘤细胞的S％,分裂增殖指数和肿瘤患者的复发和(或)转移率显著高于二倍体肿瘤者(P<0.025);患者的生存率显著低于二倍体肿瘤者(P<0.025)。表明:肿瘤细胞核DNA测定能提供重要的预后信息,有助于改进治疗,提高患者生存率。 The authors determined the amount of nuclear DNA in cancer cells by flow cytometry in 41 patients with laryngeal squamous cell carcinoma who underwent surgical treatment and followed up for more than 2 years. Results: The heteroploidy rate was 65.85%. The S% of the aneuploid tumor cells, the proliferative index of metastasis, and the recurrence and/or metastasis rate of tumor patients were significantly higher than those of diploid tumors (P<0.025); the survival rate of patients was significantly lower than that of diploid tumors ( P<0.025). It shows that the determination of tumor nuclear DNA can provide important prognostic information, help improve the treatment, and improve patient survival.