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高级别宫颈上皮内瘤变(cervical intraepithelial neoplasia,CIN)采用物理治疗或手术切除后,仍然存在复发的风险。CIN术后复发主要与手术方式、手术切缘状况、累及腺体、人乳头瘤病毒(HPV)持续感染以及局部免疫状态有关,年龄可作为一个术前预测指标。术后严密随访,及早确诊病灶残留或复发,采用扩大切除范围或行全子宫切除,避免漏诊和过度治疗。
High risk of cervical intraepithelial neoplasia (CIN) after physical therapy or surgical resection, there is still the risk of recurrence. Recurrence of CIN is mainly related to the surgical method, surgical margins, involvement of the gland, persistent infection of human papillomavirus (HPV) and local immune status. Age can be used as a preoperative prediction index. Follow-up after surgery, early diagnosis of residual disease or recurrence, the use of extended resection or hysterectomy line to avoid misdiagnosis and over-treatment.