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目的评价WHOQOL HIV-BREF量表用于评价经高效抗反转录病毒治疗(HARRT)的艾滋病(AIDS)病人的信度、效度。方法 2008年7月-2009年6月,使用AIDS病人生存质量调查表,对102例确诊的AIDS病人进行调查,内容包括HIV-BREF量表、基本人口学资料以及AIDS相关症状等;采用相关分析、信度分析、因子分析和方差分析等统计方法考察量表的信度、效度和区分度。结果 HIV-BREF量表每个领域的分半信度和内部一致性信度系数>0.60,重测信度系数>0.50。每个条目跟相关领域的相关系数都>0.54(有统计学意义),大于该条目与其他领域的相关系数。因子分析提取的6个主成分分别代表了各个领域,累计贡献达到72.46%;其结果与量表的理论结构假设基本一致。HIV-BREF量表能够区分是否吸毒、不同感染阶段病人的生存质量,具有较好的区分度。结论 HIV-BREF量表有较好的信度、效度和区分度,在临床以及科研中,可用于评价AIDS病人的生存质量。
Objective To evaluate the WHOQOL HIV-BREF scale for assessing the reliability and validity of AIDS patients with highly effective antiretroviral therapy (HARRT). Methods From July 2008 to June 2009, 102 HIV-infected AIDS patients were investigated using the AIDS Patient Quality of Life Questionnaire, including HIV-BREF scale, basic demographic data and AIDS-related symptoms. Correlation analysis was performed using correlation analysis , Reliability analysis, factor analysis and analysis of variance and other statistical methods to examine the scale of reliability, validity and differentiation. Results The half-confidence level and internal consistency reliability coefficient of each field of HIV-BREF scale were> 0.60, and the test-retest reliability coefficient> 0.50. Each entry has a correlation coefficient of> 0.54 (statistically significant) with the relevant area, greater than the correlation coefficient of the entry with other areas. The six principal components extracted from factor analysis represent the various fields respectively, with a total contribution of 72.46%. The results are basically consistent with the theoretical structure of the scale. HIV-BREF scale to distinguish whether drug abuse, different stages of infection quality of life of patients with better discrimination. Conclusion The HIV-BREF scale has good reliability, validity and discrimination. It can be used to evaluate the quality of life of AIDS patients in clinical and scientific research.